海风藤酮治疗大鼠实验性急性胰腺炎

【关键词】 胰腺炎；血小板活化因子；海风藤酮；肿瘤坏死因子；白细胞介素
　　Role of kadsurenone in treatment of experimental acute pancreatitis in rats
　　【Abstract】 AIM: To explore the effect of kadsurenone on inflammatory mediators in rats during acute pancreatitis (AP). METHODS: A total of 104 SD male rats which weighed 250-300 g were randomly divided into sham group (n=24), AP group (n=40) and kadsurenone group (n=40). The animals in the groups were killed in 3, 6, 12, 24 h after operation for experimental observation. RESULTS: The serum levels of PAF, TNFα and IL6 of AP rats significantly increased （P